Pathology: leiomyoma
Leiomyoma
Interwoven fascicles of spindle cells
Bright eosinophilic cytoplasm with occasional perinuclear vacuoles
Ovoid and elongated nuclei with rounded ends; inconspicuous mitotic activity
Occasional basophilic ovoid intracytoplasmic structures (corpora amylacea)
PMID: 23833049
Leiomyoma
Circumscribed; interwoven fascicles of spindle cells
Bright eosinophilic cytoplasm with occasional perinuclear vacuoles
Ovoid and elongated nuclei with rounded ends; inconspicuous mitotic activity
Prominent basophilic ovoid intracytoplasmic structures (corpora amylacea)
PMID: 23833049
Leiomyoma
Interwoven fascicles of spindle cells
Bright eosinophilic cytoplasm with occasional perinuclear vacuoles
Ovoid and elongated nuclei with rounded ends; inconspicuous mitotic activity
IHC: H-caldesmon
Leiomyoma
Interwoven fascicles of spindle cells
Bright eosinophilic cytoplasm with occasional perinuclear vacuoles
Ovoid and elongated nuclei with rounded ends; inconspicuous mitotic activity
IHC: H-caldesmon
Leiomyoma
Interwoven fascicles of spindle cells
Bright eosinophilic cytoplasm with occasional perinuclear vacuoles
Ovoid and elongated nuclei with rounded ends; inconspicuous mitotic activity
IHC: H-caldesmon
Leiomyoma, fumarate hydratase-deficient
Multinodular; fascicles of spindle cells
Abundant eosinophilic cytoplasm
Ovoid nuclei and small nucleoli with occasional perinucleolar halo; inconspicuous mitotic activity
IHC: H-caldesmon, fumarate hydratase
DNA-seq: FH p.S334R SNV