Pathology: angiomyofibroblastoma

Angiomyofibroblastoma

  • Circumscribed; variable cellularity

  • Spindle-epithelioid cells with haphazard pattern (the latter tends to concentrate around vessels)

  • Eosinophilic cytoplasm with delicate tapering processes

  • Ovoid-round nuclei with occasional bi- and multi-nucleation; inconspicuous mitotic activity

  • Oedematous stroma with abundant wavy collagen bundles and occasional mast cells; prominent small, ectatic thin-walled vessels

  • IHC: desmin

Angiomyofibroblastoma

  • Circumscribed with thin fibrous pseudocapsule; variable cellularity

  • Spindle-epithelioid cells with haphazard pattern (the latter tends to concentrate around vessels)

  • Eosinophilic cytoplasm with delicate tapering processes

  • Ovoid-round nuclei with occasional bi- and multi-nucleation; inconspicuous mitotic activity

  • Oedematous stroma with coarse collagen bundles; prominent small, ectatic vessels with hyalinized walls

These tumours typically express desmin