Pathology: angioleiomyoma

Angioleiomyoma, solid variant

  • Circumscribed; fascicles of spindle cells

  • Abundant bright eosinophilic cytoplasm with occasional perinuclear vacuoles

  • Small ovoid nuclei with minimal atypia; inconspicuous mitotic activity

  • Slit-like vascular channels

  • IHC: desmin, smooth muscle actin, H-caldesmon

Angioleiomyoma, solid variant

  • Circumscribed; fascicles of spindle cells

  • Abundant bright eosinophilic cytoplasm with occasional perinuclear vacuoles

  • Small ovoid nuclei with minimal atypia; inconspicuous mitotic activity

  • Slit-like vascular channels; focal dystrophic calcification

  • IHC: H-caldesmon

Angioleiomyoma, venous variant

  • Interwoven fascicles of spindle cells

  • Abundant bright eosinophilic cytoplasm with occasional perinuclear vacuoles

  • Small ovoid nuclei with minimal atypia; inconspicuous mitotic activity

  • Thick muscular vascular channels

  • IHC: H-caldesmon