Pathology: tenosynovial giant cell tumour

Tenosynovial giant cell tumour, localized

  • Circumscribed; sheets of polygonal cells

  • Abundant pale eosinophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells

  • Occasional collagen bands

Tenosynovial giant cell tumour, localized

  • Circumscribed; sheets of polygonal cells

  • Abundant pale amphophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells; aggregates of siderophages; haemosiderin deposition

  • Occasional collagen bands

Tenosynovial giant cell tumour, localized

  • Circumscribed; sheets of polygonal cells

  • Abundant pale amphophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells; sheets of siderophages; haemosiderin deposition

  • Occasional collagen bands

Tenosynovial giant cell tumour, localized

  • Circumscribed; sheets of polygonal cells

  • Abundant pale eosinophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition

  • Occasional collagen bands

Tenosynovial giant cell tumour, localized

  • Circumscribed; sheets of polygonal cells

  • Abundant pale eosinophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells

  • Occasional collagen bands

Tenosynovial giant cell tumour, diffuse

  • Infiltrative; sheets of polygonal cells

  • Abundant pale eosinophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition

  • Occasional collagen bands


Tenosynovial giant cell tumour, diffuse

  • Infiltrative; sheets of polygonal cells

  • Abundant pale eosinophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition

  • Occasional collagen bands

Tenosynovial giant cell tumour, diffuse

  • Infiltrative; sheets of polygonal cells

  • Abundant pale eosinophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition

  • Occasional collagen bands

Tenosynovial giant cell tumour, diffuse

  • Infiltrative; sheets of polygonal cells

  • Abundant pale eosinophilic cytoplasm

  • Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity

  • Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition

  • Cleft-like synovial-lined spaces