Pathology: tenosynovial giant cell tumour
Tenosynovial giant cell tumour, localized
Circumscribed; sheets of polygonal cells
Abundant pale eosinophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells
Occasional collagen bands
Tenosynovial giant cell tumour, localized
Circumscribed; sheets of polygonal cells
Abundant pale amphophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells; aggregates of siderophages; haemosiderin deposition
Occasional collagen bands
Tenosynovial giant cell tumour, localized
Circumscribed; sheets of polygonal cells
Abundant pale amphophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells; sheets of siderophages; haemosiderin deposition
Occasional collagen bands
Tenosynovial giant cell tumour, localized
Circumscribed; sheets of polygonal cells
Abundant pale eosinophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition
Occasional collagen bands
Tenosynovial giant cell tumour, localized
Circumscribed; sheets of polygonal cells
Abundant pale eosinophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells
Occasional collagen bands
Tenosynovial giant cell tumour, diffuse
Infiltrative; sheets of polygonal cells
Abundant pale eosinophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition
Occasional collagen bands
Tenosynovial giant cell tumour, diffuse
Infiltrative; sheets of polygonal cells
Abundant pale eosinophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition
Occasional collagen bands
Tenosynovial giant cell tumour, diffuse
Infiltrative; sheets of polygonal cells
Abundant pale eosinophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition
Occasional collagen bands
Tenosynovial giant cell tumour, diffuse
Infiltrative; sheets of polygonal cells
Abundant pale eosinophilic cytoplasm
Monomorphic round-reniform nuclei with small nucleoli; inconspicuous mitotic activity
Irregularly interspersed osteoclast-like giant cells; aggregates of foamy macrophages, siderophages, and haemosiderin deposition
Cleft-like synovial-lined spaces