Pathology: superficial CD34-positive fibroblastic tumour
Superficial CD34-positive fibroblastic tumour
Superficial CD34-positive fibroblastic tumour
Relatively circumscribed; vague fascicles of spindle-epithelioid cells
Abundant 'glassy' eosinophilic cytoplasm
Ovoid nuclei with marked pleomorphism and occasional macro-nucleoli; atypical mitotic figure
Collagenous stroma with intermixed adipocytes and chronic inflammation
IHC: CD34
RNA-seq: negative
Superficial CD34-positive fibroblastic tumour
Superficial CD34-positive fibroblastic tumour
Relatively circumscribed; fascicles of spindle-epithelioid cells
Abundant "glassy" eosinophilic cytoplasm
Ovoid nuclei with moderate pleomorphism, occasional pseudonuclear inclusions and macronucleoli; inconspicuous mitotic activity
Focal bands of collagenous stroma; mild chronic inflammatory infiltrate
IHC: CD34, keratin (AE1/AE3)
RNA-seq: negative