Pathology: cellular angiofibroma

Cellular angiofibroma

  • Circumscribed; mild-moderate cellularity; spindle cells with loose fascicular pattern

  • Scant eosinophilic cytoplasm

  • Ovoid nuclei with areas of palisading; inconspicuous mitotic activity

  • Abundant delicate collagen fibres; prominent ectatic small-medium sized thick-walled vessels

  • IHC: CD34, RB1

Cellular angiofibroma

  • Circumscribed; mild-moderate cellularity; spindle cells with loose fascicular pattern

  • Scant amphophilic cytoplasm

  • Ovoid nuclei with areas of palisading; inconspicuous mitotic activity

  • Delicate collagen fibres; prominent ectatic small-medium sized vessels with hyalinized walls; aggregates of mature adipocytes

  • IHC: CD34

Cellular angiofibroma

  • Circumscribed; mild-moderate cellularity; spindle cells with loose fascicular pattern

  • Scant amphophilic cytoplasm

  • Ovoid nuclei with areas of palisading; inconspicuous mitotic activity

  • Delicate collagen fibres; prominent ectatic small-medium sized vessels with hyalinized walls

  • IHC: CD34, RB1