Pathology: angiolipoma
Angiolipoma
Angiolipoma
Typically small, subcutaneous and tender
Sheets of adipocytes with abundant clear cytoplasm and minimal variability in size and shape
Peripherally located small monomorphic nuclei
Prominent capillary-sized vessels with fibrin thrombi
Molecular pathogenesis distinct from conventional lipoma (PMID: 9130991)
Angiolipoma
Angiolipoma
Sheets of adipocytes with abundant clear cytoplasm and minimal variability in size and shape
Small monomorphic nuclei
Peripherally there is a prominent capillary-sized vasculature; conspicuous fibrin thrombi